Vitamin B-6 Dependency Syndromes Medication

Updated: Oct 19, 2022
  • Author: Haritha Reddy Chelimilla, MD; Chief Editor: Jatinder Bhatia, MBBS, FAAP  more...
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Class Summary

These agents are organic substances required by the body in small amounts for various metabolic processes. Vitamins may be synthesized in small or insufficient amounts in the body or not synthesized at all, thus requiring supplementation. Deficiency may result from an inadequate diet, increased requirements, or secondary to disease or drugs. They are used clinically for the prevention and treatment of specific vitamin deficiency states and are considered third-line treatment for both acute and chronic intractable seizure disorders in children younger than 2 years.

Pyridoxine (Vitamin B-6)

Necessary for normal metabolism of proteins, carbohydrates, and fats. Also involved in synthesis of GABA within the CNS. Indicated to treat pyridoxine-dependent disorders caused by enzyme deficiency or deficiency in enzyme activity. These disorders are responsive to pyridoxine administration, typically in high doses.