Pediatric Medullary Sponge Kidney Medication

Updated: Aug 28, 2021
  • Author: Howard Trachtman, MD; Chief Editor: Craig B Langman, MD  more...
  • Print

Medication Summary

No medications are warranted for routine care of medullary sponge kidney (MSK). Oral potassium citrate may reduce the incidence of kidney stones in the subset of patients with medullary sponge kidney who are at risk for this complication. Use antibiotics in accordance with standard prescription practices to treat urinary tract infections (UTIs). See Urinary Tract Infection. Consider thiazide diuretics in patients with hypercalciuric urolithiasis.



Class Summary

Thiazide diuretics may be prescribed to patients who have medullary sponge kidney and hypercalciuria, with or without urolithiasis.

Hydrochlorothiazide (Esidrix, HydroDIURIL, Microzide)

Decreases hypercalciuria and reduces risk of urolithiasis by promoting calcium reabsorption in distal convoluted tubule.