Pediatric Protein-Losing Enteropathy Medication

Updated: Jul 25, 2017
  • Author: Simon S Rabinowitz, MD, PhD, FAAP; Chief Editor: Carmen Cuffari, MD  more...
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Class Summary

In protein-losing enteropathy (PLE) related to lymphatic pathology, providing supplementation with fat-soluble vitamins (eg, A, D, E, K) is important. These agents are necessary for growth and health. For healthy individuals, they are needed in small amounts only and are available in the foods of a daily diet. However, soluble vitamin supplementation is essential in patients with protein-losing enteropathy because the small amounts available in a regular diet are insufficient in the face of the malabsorption that occurs.

ADEK vitamins (AquADEKs Pediatric Liquid, ADEKs Chewable)

PO multinutrient specially formulated for use under medical supervision to provide nutritional supplementation in individuals with malabsorptive conditions. Each 1 mL dose contains water-miscible forms of fat-soluble vitamins A (5,751 U), D (400 U), E (65 U), and K (400 mcg) plus other nutrients, including vitamin C (15 mcg), B-complex vitamins, biotin, selenium (10 mcg), and zinc gluconate (5 mg). Available as chewable tab or pediatric drops.

Vitamin A (Aquasol A)

Needed for night vision and growth of skin, bones, male reproductive organs, and female reproductive organs.

Ergocalciferol (Calciferol, Drisdol)

Form of vitamin D used in vitamin supplements, necessary for strong bones and teeth.

Vitamin E (Vita-Plus E Softgels, Vitec)

Protects polyunsaturated fatty acids in membranes from attack by free radicals and protects red blood cells against hemolysis.

Vitamin K (AquaMEPHYTON)

Fat-soluble vitamin absorbed by the gut and stored in the liver; necessary for the function of clotting factors in the coagulation cascade; used to replace essential vitamins not obtained in sufficient quantities in the diet or to further supplement levels.