Pediatric Growth Hormone Deficiency Medication

Updated: Aug 22, 2018
  • Author: Vaneeta Bamba, MD; Chief Editor: Robert P Hoffman, MD  more...
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Medication Summary

Growth hormone replacement is used to treat growth hormone deficiency (GHD).


Growth hormones

Class Summary

These agents are used for physiologic replacement.

Somatropin (Genotropin, Humatrope, Norditropin, Nutropin, Omnitrope, Saizen, TevTropin)

Purified polypeptide hormone of recombinant DNA origin. In children whose epiphyses are not yet fused, GH replacement usually causes significant increase in growth velocity (averaging 10-11 cm/y during first y of therapy). Response wanes each y, but growth velocity continues at faster than pretreatment rates. A long-acting depot preparation designed for monthly or bimonthly SC injection was available but is not off the market. Other long-acting preparations are currently under investigation.