Gianotti-Crosti Syndrome Medication

Updated: Oct 09, 2020
  • Author: Sören A Craig-Müller, MD; Chief Editor: Dirk M Elston, MD  more...
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Medication Summary

No medical therapy is necessary. Topical corticosteroids and oral antihistamines might provide some symptomatic relief of pruritus.


Corticosteroids, topical cream

Class Summary

These agents may provide relief when pruritus is present.

Triamcinolone topical (Aristocort)

The antipruritic effect of this cream is fairly marginal but may be somewhat effective. It treats inflammatory dermatoses that are responsive to steroids. Triamcinolone topical decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.



Class Summary

These agents may provide some relief when pruritus is present. They are used to treat minor allergic reactions and anaphylaxis and may be used to pretreat patients with prior documentation of minor allergic reactions. These agents may control itching by blocking effects of endogenously released histamine.

Hydroxyzine (Atarax, Vistaril)

Hydroxyzine offers a mild degree of relief from pruritus. It antagonizes H1 receptors in the periphery. Hydroxyzine may suppress histamine activity in the subcortical region of the CNS.