Medication Summary
No medical therapy is necessary. Topical corticosteroids and oral antihistamines might provide some symptomatic relief of pruritus.
Corticosteroids, topical cream
Class Summary
These agents may provide relief when pruritus is present.
Triamcinolone topical (Aristocort)
The antipruritic effect of this cream is fairly marginal but may be somewhat effective. It treats inflammatory dermatoses that are responsive to steroids. Triamcinolone topical decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.
Antihistamines
Class Summary
These agents may provide some relief when pruritus is present. They are used to treat minor allergic reactions and anaphylaxis and may be used to pretreat patients with prior documentation of minor allergic reactions. These agents may control itching by blocking effects of endogenously released histamine.
Hydroxyzine (Atarax, Vistaril)
Hydroxyzine offers a mild degree of relief from pruritus. It antagonizes H1 receptors in the periphery. Hydroxyzine may suppress histamine activity in the subcortical region of the CNS.
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Multiple erythematous flat-topped papules on the cheeks of an 18-month-old boy with Gianotti-Crosti syndrome.
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Arm of a 3-year-old boy with Gianotti-Crosti syndrome demonstrating well-defined erythematous lichenoid papules on the arm and forearm.
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Thigh of the 3-year-old boy with Gianotti-Crosti syndrome.