Supraglottic Cancer Guidelines

1. Jackson C. Malignant diseases of the epiglottis. Peroral Endoscopy and Laryngeal Surgery. 1915. 438-9.

2. Alonso J. Conservation surgery of cancer of the larynx. Am Acad Ophthalmol Otolaryngol. 1947 Jul-Aug.

3. Ogura JH. Supraglottic subtotal laryngectomy and radical neck dissection for carcinoma of the epiglottis. Laryngoscope. 1958 Jun. 68(6):983-1003. [QxMD MEDLINE Link].

4. Chu EA, Young JK. Laryngeal cancer: diagnosis and pre-operative work-up. Otolaryngol Clin N Am. 2008. 41:673-695.

5. Parkin DM, Bray F, Ferlay J, et al. Global cancer statistics, 2002. CA Cancer J Clin. 2005 Mar-Apr. 55(2):74-108. [QxMD MEDLINE Link].

6. Morales-Angulo C, Val-Bernal F, Buelta L, et al. Prognostic factors in supraglottic laryngeal carcinoma. Otolaryngol Head Neck Surg. 1998 Nov. 119(5):548-53. [QxMD MEDLINE Link].

7. De Stefani E, Boffetta P, Deneo-Pellegrini H, et al. Supraglottic and glottic carcinomas: epidemiologically distinct entities?. Int J Cancer. 2004 Dec 20. 112(6):1065-71. [QxMD MEDLINE Link].

8. Slaughter D. Multicentric origin of intra-oral carcinoma. Surgery. 1946. 20:133-46.

9. Lin JY, Li XY, Dong P, Nakashima T. Prognostic value of lymphangiogenesis in supraglottic laryngeal carcinoma. J Laryngol Otol. 2011 Sep. 125(9):945-51. [QxMD MEDLINE Link].

10. Lopchinsky RA, Amog-Jones GF, Pathi R. Ultrasound-guided fine needle aspiration diagnosis of supraglottic laryngeal cancer. Head Neck. 2011 Aug 8. [QxMD MEDLINE Link].

11. National Comprehensive Cancer Network. National Comprehensive Cancer Network Practice Guidelines in Oncology, v.2.2008, Section: SUPRA. [Full Text].

12. The Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med. 1991 Jun 13. 324(24):1685-90. [QxMD MEDLINE Link].

13. Forastiere AA, Goepfert H, Maor M, et al. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med. 2003 Nov 27. 349(22):2091-8.

14. Reizenstein JA, Holmberg L, Bergqvist M, Linder A, Ekman S, Lödén B, et al. Time trends in T3-4 laryngeal cancer - a population based long term analysis. Head Neck. 2013 Oct 25. [QxMD MEDLINE Link].

15. Liu YH, Du ZW. Management of clinically negative nodes (N0) in supraglottic laryngeal carcinoma: A systematic review. Genet Mol Res. 2016 Oct 17. 15 (4):[QxMD MEDLINE Link].

16. Yılmaz T, Suslu N, Atay G, Gunaydın RO, Bajin MD, Ozer S. The effect of midline crossing of lateral supraglottic cancer on contralateral cervical lymph node metastasis. Acta Otolaryngol. 2015 May. 135 (5):484-8. [QxMD MEDLINE Link].

17. Grant DG, Salassa JR, Hinni ML, et al. Transoral laser microsurgery for carcinoma of the supraglottic larynx. Otolaryngol Head Neck Surg. 2007 Jun. 136(6):900-6. [QxMD MEDLINE Link].

18. Csanády M, Czigner J, Vass G, Jóri J. Transoral CO2 laser management for selected supraglottic tumors and neck dissection. Eur Arch Otorhinolaryngol. 2011 Aug. 268(8):1181-6. [QxMD MEDLINE Link].

19. Suárez C, Rodrigo JP, Silver CE, Hartl DM, Takes RP, Rinaldo A, et al. Laser surgery for early to moderately advanced glottic, supraglottic, and hypopharyngeal cancers. Head Neck. 2011 Apr 15. [QxMD MEDLINE Link].

20. Fink DS, Sibley H, Kunduk M, et al. Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2016 Oct. 155 (4):606-11. [QxMD MEDLINE Link].

21. Peretti G, Piazza C, Penco S, et al. Transoral laser microsurgery as primary treatment for selected T3 glottic and supraglottic cancers. Head Neck. 2016 Jul. 38 (7):1107-12. [QxMD MEDLINE Link].

22. Peretti G, Piazza C, Mora F, Garofolo S, Guastini L. Reasonable limits for transoral laser microsurgery in laryngeal cancer. Curr Opin Otolaryngol Head Neck Surg. 2016 Apr. 24 (2):135-9. [QxMD MEDLINE Link].

23. Agrawal A, Moon J, Davis RK, et al. Transoral carbon dioxide laser supraglottic laryngectomy and irradiation in stage I, II, and III squamous cell carcinoma of the supraglottic larynx: report of Southwest Oncology Group Phase 2 Trial S9709. Arch Otolaryngol Head Neck Surg. 2007 Oct. 133(10):1044-50. [QxMD MEDLINE Link].

24. Cabanillas R, Rodrigo JP, Llorente JL, et al. Oncologic outcomes of transoral laser surgery of supraglottic carcinoma compared with a transcervical approach. Head Neck. 2008 Jun. 30(6):750-5. [QxMD MEDLINE Link].

25. Rodrigo JP, Cabanillas R, Franco V, et al. Efficacy of routine bilateral neck dissection in the management of the N0 neck in T1-T2 unilateral supraglottic cancer. Head Neck. 2006 Jun. 28(6):534-9. [QxMD MEDLINE Link].

26. Sevilla MA, Rodrigo JP, Llorente JL, et al. Supraglottic laryngectomy: analysis of 267 cases. Eur Arch Otorhinolaryngol. 2008 Jan. 265(1):11-6. [QxMD MEDLINE Link].

27. Dünne AA, Davis RK, Dalchow CV, et al. Early supraglottic cancer: how extensive must surgical resection be, if used alone?. J Laryngol Otol. 2006 Sep. 120(9):764-9. [QxMD MEDLINE Link].

28. Cagli S, Yuce I, Yigitbasi OG, et al. Is routine bilateral neck dissection absolutely necessary in the management of N0 neck in patients with supraglottic carcinoma?. Eur Arch Otorhinolaryngol. 2007 Dec. 264(12):1453-7. [QxMD MEDLINE Link].

29. Carta F, Mariani C, Sambiagio GB, et al. CO₂ Transoral Microsurgery for Supraglottic Squamous Cell Carcinoma. Front Oncol. 2018. 8:321. [QxMD MEDLINE Link]. [Full Text].

30. Brandstorp-Boesen J, Sorum Falk R, Folkvard Evensen J, Boysen M, Brondbo K. Risk of Recurrence in Laryngeal Cancer. PLoS One. 2016. 11 (10):e0164068. [QxMD MEDLINE Link]. [Full Text].

31. Nicolai P, Redaelli de Zinis LO, Tomenzoli D, et al. Prognostic determinants in supraglottic carcinoma: univariate and Cox regression analysis. Head Neck. 1997 Jul. 19(4):323-34. [QxMD MEDLINE Link].

32. Petrakos I, Kontzoglou K, Nikolopoulos TP, Papadopoulos O, Kostakis A. Glottic and supraglottic laryngeal cancer: epidemiology, treatment patterns and survival in 164 patients. J BUON. 2012 Oct-Dec. 17(4):700-5. [QxMD MEDLINE Link].

33. Patel TD, Echanique KA, Yip C, et al. Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases. Laryngoscope. 2018 Dec 11. [QxMD MEDLINE Link].

34. Carvalho AL, Nishimoto IN, Califano JA, Kowalski LP. Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer. 2005 May 1. 114 (5):806-16. [QxMD MEDLINE Link]. [Full Text].

35. Hoffman HT, Porter K, Karnell LH, et al. Laryngeal cancer in the United States: changes in demographics, patterns of care, and survival. Laryngoscope. 2006 Sep. 116(9 Pt 2 Suppl 111):1-13. [QxMD MEDLINE Link].

36. Cosetti M, Yu GP, Schantz SP. Five-year survival rates and time trends of laryngeal cancer in the US population. Arch Otolaryngol Head Neck Surg. 2008 Apr. 134(4):370-9. [QxMD MEDLINE Link].

37. Elegbede AI, Rybicki LA, Adelstein DJ, et al. Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx. JAMA Otolaryngol Head Neck Surg. 2015 May 7. [QxMD MEDLINE Link].

38. [Guideline] Jones TM, De M, Foran B, Harrington K, Mortimore S. Laryngeal cancer: United Kingdom National Multidisciplinary guidelines. J Laryngol Otol. 2016 May. 130 (S2):S75-S82. [QxMD MEDLINE Link]. [Full Text].

39. Lechien JR, Fakhry N, Saussez S, et al. Surgical, clinical and functional outcomes of transoral robotic surgery for supraglottic laryngeal cancers: a systematic review. Oral Oncol. 2020 Jun 10. 109:104848. [QxMD MEDLINE Link].

Joshua D Hornig, MD, FRCSC Head and Neck Specialists - Charleston

Joshua D Hornig, MD, FRCSC is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Head and Neck Society, American Medical Association, Canadian Medical Association, Canadian Society of Otolaryngology-Head & Neck Surgery, Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Christina ST Wilhoit, CRA, BA, CCRP Head and Neck Specialists - Charleston

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Nader Sadeghi, MD, FRCSC Professor and Chairman, Department of Otolaryngology-Head and Neck Surgery, McGill University Faculty of Medicine; Chief Otolaryngologist, MUHC; Director, McGill Head and Neck Cancer Program, Royal Victoria Hospital, Canada

Nader Sadeghi, MD, FRCSC is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Head and Neck Society, American Thyroid Association, Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Arlen D Meyers, MD, MBA Professor of Otolaryngology, Dentistry, and Engineering, University of Colorado School of Medicine

Arlen D Meyers, MD, MBA is a member of the following medical societies: American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Otolaryngology-Head and Neck Surgery, American Head and Neck Society

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Cerescan, Ryte, Neosoma, MI10<br/>Received income in an amount equal to or greater than $250 from: , Cliexa;;Neosoma<br/> Received ownership interest from Cerescan for consulting; for: Neosoma, eMedevents, MI10.

Steven D Schaefer, MD, FACS Professor, Department of Otolaryngology, New York Medical College; Director of Center for Nasal-Sinus Disease and Academics, New York Head and Neck Institute Service Line of Northwell Health

Steven D Schaefer, MD, FACS is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Cancer Society, American College of Surgeons, American Head and Neck Society, American Laryngological Association, American Medical Association, American Rhinologic Society, New York Academy of Medicine, New York County Medical Society, Society of University Otolaryngologists-Head and Neck Surgeons, The Triological Society

Disclosure: Nothing to disclose.

M Abraham Kuriakose, MD, DDS, FRCS Chairman, Head and Neck Institute, Amrita Institute of Medical Sciences

M Abraham Kuriakose, MD, DDS, FRCS is a member of the following medical societies: American Association for Cancer Research, American Head and Neck Society, British Association of Oral and Maxillofacial Surgeons, Royal College of Surgeons of England

Disclosure: Nothing to disclose.

Jonathan E Sonne, MD Consulting Staff, Department of Facial Plastic and Reconstructive Surgery, The Woodruff Institute

Jonathan E Sonne, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Cosmetic Surgery, American Academy of Facial Plastic and Reconstructive Surgery, American Medical Association, and Florida Medical Association

Disclosure: Nothing to disclose.

• Print this section
• Print the entire contents of
• Print the entire contents of article