Chloropicrin Poisoning Clinical Presentation

Updated: Mar 15, 2022
  • Author: Kermit D Huebner, MD, FACEP; Chief Editor: Zygmunt F Dembek, PhD, MS, MPH, LHD  more...
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Clinicians should attempt to elicit an accurate history to involve the setting of exposure. This may occur as an occupational exposure, as an intentional and unintentional industrial release, or as a terrorist attack.



Physical manifestations depend on the route of exposure.

  • Skin - Evidence of chemical burns or dermatitis manifested by red, cracked, irritated, or bluish skin
  • Eyes - Pain, redness, and tearing
  • Respiratory - Coughing, labored breathing, rales, and rhonchi

In the large-scale exposure that occurred in Kern County, California, exposed persons reported the following signs and symptoms [4] :

  • Eye pain, burning, or lacrimation (in 99% of cases)
  • Respiratory symptoms, including cough, dyspnea, or upper respiratory irritation (51%)
  • Gastrointestinal complaints such as nausea, vomiting, abdominal pain, or diarrhea (47%)
  • Headache (25%)