Vitamin Toxicity Differential Diagnoses

Updated: Oct 20, 2021
  • Author: Mark Rosenbloom, MD, MBA; Chief Editor: Michael A Miller, MD  more...
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Diagnostic Considerations

Differential diagnosis in vitamin toxicity can include the following:

  • Ciguatera toxicity
  • Fluoride toxicity
  • Iron toxicity
  • Osgood-Schlatter disease

Vitamin E

An elevated international normalized ratio (INR) may result from excessive doses of warfarin anticoagulants. Vitamin K deficiency and liver failure can prolong the prothrombin time (PT) and raise the INR.

Vitamin A

The skin pigmentation seen in carotenemia is also observed with the consumption of large amounts of colored fruits and vegetables.

Differential Diagnoses