Rodenticide Toxicity Differential Diagnoses

Updated: Nov 20, 2019
  • Author: Derrick Lung, MD, MPH, FACEP, FACMT; Chief Editor: Asim Tarabar, MD  more...
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Diagnostic Considerations

Congenital deficiency in clotting factor VII may present with bleeding associated with an abnormal prothrombin time (PT) but a normal activated partial thromboplastin time (aPTT). At first, this may appear to be anticoagulation from a rodenticide or Coumadin; however, with the marked prolongation in PT, some abnormality in aPTT should be present, except in specific factor VII deficiency.

Conditions to consider in the differential diagnosis of rodenticide exposure include the following:

  • Acute respiratory distress syndrome
  • Ammonia toxicity
  • Arsenic toxicity
  • Chlorine Gas toxicity
  • Clonidine toxicity
  • Cyanide toxicity
  • Fluoride toxicity
  • Hydrogen sulfide toxicity

Differential Diagnoses