Licorice Poisoning Differential Diagnoses

Updated: Apr 11, 2022
  • Author: Seth Schonwald, MD, FACEP; Chief Editor: Sage W Wiener, MD  more...
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Diagnostic Considerations

Other causes of hypokalemia to be considered include the following:

  • Aminoglycosides
  • Barium poisoning
  • Beta-adrenergic agonists
  • Diarrhea
  • Diuretics
  • Enemas or laxative use
  • Hyperaldosteronism
  • Ileal loop
  • Insulin
  • Leukemia
  • Magnesium depletion
  • Periodic hypokalemic paralysis
  • Steroids
  • Theophylline

Other causes of hyperaldosteronism to be considered include the following:

  • Bartter syndrome (ie, hyperaldosteronism, hyperreninism, hypokalemic acidosis)
  • Bilateral adrenal hyperplasia
  • Ectopic adrenocorticotropic hormone (ACTH) syndrome (eg, Wilms tumor)
  • Hypertensive urgencies

Excess licorice consumption can result in salt retention, hypokalemia, hypertension, metabolic alkalosis, hypoaldosteronism,and low renin activity.  These symptoms mimic those of mineralocorticoid excess syndrome (eg, congenital adrenal hyperplasia). [27]

Differential Diagnoses