Tropane Alkaloid Poisoning Workup

Updated: Sep 18, 2019
  • Author: Richard A Wagner, MD, PhD, FACEP, FAAEM; Chief Editor: Asim Tarabar, MD  more...
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Laboratory Studies

No specific diagnostic studies for tropane alkaloid poisonings exist. Tropane alkaloids are not included in standard drugs of abuse or comprehensive toxicology panels; serum drug concentrations are neither helpful nor readily available to aid in initial management.

Since acetaminophen and salicylate are common co-ingestants in many poisonings, consider assays for acetaminophen and salicylate levels. In febrile patients, consider blood and urine cultures. Serum electrolyte levels may provide insight into other intoxicating agents and co-ingestants.

Consider a pregnancy test for all female patients of childbearing age.


Imaging Studies

Consider CT scan of the head for patients with altered mental status that is inadequately explained by toxicity from ingested agent or is unresponsive to appropriate intervention.


Other Tests

Obtain an electrocardiogram (ECG) at presentation for all patients with suspected toxic ingestions.



Consider lumbar puncture (LP) for patients with fever and altered mental status.

Consider invasive monitoring for hemodynamically unstable patients.