Phencyclidine Toxicity Differential Diagnoses

Updated: Mar 28, 2022
  • Author: Patrick L West, MD; Chief Editor: Michael A Miller, MD  more...
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Diagnostic Considerations

The acute toxicity of phencyclidine (PCP) is often misdiagnosed because of its similarity to schizophrenic episodes. In fact, PCP-induced psychosis may respond to antipsychotics, which may further confound the diagnosis. Other problems to be considered in the differential diagnosis of PCP toxicity include the following:

  • Lysergic acid diethylamide (LSD) toxicity
  • Plant poisoning, mescaline
  • Malignant hyperthermia
  • Serotonin syndrome

Differential Diagnoses