Hyperviscosity Syndrome Questions & Answers

Updated: Dec 11, 2019
  • Author: Thomas J Hemingway, MD, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Questions & Answers

Overview

What is hyperviscosity syndrome (HVS)?

What is the clinical presentation of hyperviscosity syndrome (HVS)?

How is the diagnosis of hyperviscosity syndrome (HVS) confirmed?

What is the initial treatment of hyperviscosity syndrome (HVS) from elevated immunoglobulin levels?

What is the definitive treatment of hyperviscosity syndrome (HVS)?

What is the pathophysiology of hyperviscosity syndrome (HVS)?

What bone marrow conditions cause hyperviscosity syndrome (HVS)?

What are the physiologic causes of the symptoms of hyperviscosity syndrome (HVS)?

What is the epidemiology of hyperviscosity syndrome (HVS)?

Presentation

What is the clinical presentation of hyperviscosity syndrome (HVS)?

What are the most common symptoms of hyperviscosity syndrome (HVS)?

What visual changes are associated with hyperviscosity syndrome (HVS)?

What other symptoms are associated with hyperviscosity syndrome (HVS)?

What are the physical findings of the major organ systems in hyperviscosity syndrome (HVS)?

What causes of hyperviscosity syndrome (HVS)?

DDX

Which neurologic signs and symptoms are associated with hyperviscosity syndrome (HVS)?

What are the diagnostic considerations for hyperviscosity syndrome (HVS)?

What are the differential diagnoses for Hyperviscosity Syndrome?

Workup

Which lab studies can confirm a diagnosis of hyperviscosity syndrome (HVS)?

What other lab testing is done to diagnose hyperviscosity syndrome (HVS)?

Which imaging studies are indicated in the workup of hyperviscosity syndrome (HVS)?

Treatment

What prehospital care is indicated for patients with hyperviscosity syndrome (HVS)?

What is the initial treatment for hyperviscosity syndrome (HVS) caused by paraproteinemia?

What treatment is indicated for patients with visual symptoms in hyperviscosity syndrome (HVS)?

What are the signs and symptoms of congestive heart failure (CHF) from hyperviscosity syndrome (HVS)?

What is the definitive treatment of hyperviscosity syndrome (HVS)?

When should a hematologist be consulted in the treatment of hyperviscosity syndrome (HVS)?

Follow-up

What inpatient care is indicated in the treatment of hyperviscosity syndrome (HVS)?

When is transfer indicated in the treatment of hyperviscosity syndrome (HVS)?

What is the prognosis of hyperviscosity syndrome (HVS)?

How should a patient be educated about hyperviscosity syndrome (HVS)?