Eosinophilic Granuloma (Histiocytosis X) Differential Diagnoses

Updated: Sep 11, 2020
  • Author: Eleanor M Summerhill, MD, FACP, FCCP; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Diagnostic Considerations

Other possible diagnoses include the following:

  • Lymphangioleiomyomatosis (LAM): Patients with pulmonary Langerhans cell histiocytosis X (PLCH) frequently present to medical attention with spontaneous pneumothoraces. Lymphangioleiomyomatosis is a disorder that exclusively affects young women and is characterized by cystic, emphysematous dilation of the terminal airways and shares this predisposition. It may be mistaken for PLCH on a chest radiograph or high-resolution CT (HRCT) scan of the chest.

  • Pulmonary histiocytic sarcoma [11]

Differential Diagnoses