Dysthymic Disorder Workup

Updated: Oct 01, 2019
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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Laboratory Studies

The following lab tests may be carried out in the evaluation of patients with dysthymia:

  • Complete blood count (CBC) with a sedimentation rate

  • Thyroid function tests

  • Homocysteine and methylmalonic acid levels - These may be better for detecting folate/vitamin B-12–responsive dysthymia than would folate and vitamin B-12 levels themselves


Imaging Studies

While functional magnetic resonance imaging (fMRI) offers promise in the differential diagnosis of dysthymia, it remains strictly a research tool.

Single-photon emission computed tomography (SPECT) scanning is being offered commercially at some centers, but the existing database on depression may not be adequate, rendering this to likely be limited to an experimental study for the depressive spectrum.