Obesity and Pregnancy Medication

Updated: Oct 18, 2021
  • Author: Dawn M Palaszewski, MD; Chief Editor: Edward H Springel, MD, FACOG  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and prevent complications.

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Antibiotics

Class Summary

Therapy must cover all likely pathogens in the context of this clinical setting. Prophylactic antibiotics should be administered based on maternal weight.

Cefazolin

First-generation semisynthetic cephalosporin that arrests bacterial cell wall synthesis, inhibiting bacterial growth. Based on general surgical procedures, the suggested recommended dose is a 2-g prophylactic dose for women who weigh >80 kg (175 lb), with an increase to 3 g for those who weight >120 kg (265 lb). Another suggested option is to repeat the dose in 4 hours.

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