Elizabethkingia Infections Workup

Updated: Feb 03, 2017
  • Author: Meenal Malviya, MBBS, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Approach Considerations

Elizabethkingia infections are diagnosed based on culture from sterile sites, usually blood. [3]

Bacterial detection software in some clinical laboratories may misidentify Elizabethkingia as other bacteria. When such cases result in identification of F meningosepticum or C meningosepticum, the CDC has advised that these results be reported to the state health department for consultation and that the infection be treated presumptively as infection with E anophelis. [3]

State clinical microbiology laboratories can characterize the isolates using pulsed-field gel electrophoresis, a method that can correctly identify the Elizabethkingia genus. Isolates sent to the CDC's Special Bacteriology Reference Laboratory are confirmed as the species E anophelis based on the pathogen's protein profile, acquired using the mass spectrometry method MALDI-ToF and optical mapping of the bacterial genome. [3]