Overview
What is the risk of Zika virus infection in the US?
Which countries have active Zika virus transmission?
Is Zika virus infection a notifiable/reportable condition?
How is Zika virus transmitted?
Which hosts are susceptible to Zika virus?
What is the structure of Zika virus?
What is the global prevalence Zika virus infection?
How is the typical course of Zika virus infection characterized?
What should travelers and new mothers know about Zika virus?
Presentation
What is the most common symptom of Zika virus infection?
How is the rash in Zika virus infection characterized?
What are the symptoms of Zika virus infection besides rash?
How common is complete recovery from Zika virus infection?
Which congenital malformations are associated with Zika virus infection?
How are newborns exposed to Zika virus monitored?
What complications are associated with Zika virus infection?
DDX
Which conditions may mimic Zika virus infection?
What are the differential diagnoses for Zika Virus?
Workup
Which lab testing is recommended in the workup of Zika virus infection?
What is the role of travel history related to Zika virus infection in pregnancy?
How is Guillain-Barré syndrome related to Zika virus infection diagnosed?
How is serologic testing used in the workup of Zika virus infection?
Which lab testing for Zika virus infection is indicated in pregnancy?
Which lab testing for Zika virus infection is indicated in congenital Zika virus infection?
Which imaging studies are indicated in the workup of Zika virus infection in pregnancy?
When is amniocentesis indicated in the workup of Zika virus infection?
Treatment
What is the treatment of Zika virus infection?
What is the treatment of Guillain-Barré syndrome associated with Zika virus infection?
When is consultation indicated in Zika virus infection?
How can Zika virus infection be prevented?
How can the spread of Zika virus be minimized?
How can Zika virus be transmitted other than by mosquito bite?
What are the travel alerts on Zika virus for pregnant women?
Is there a vaccine for Zika virus?
Guidelines
What are the CDC travel advisories on Zika virus?
What are the CDC recommendations to prevent mosquito bites and Zika virus infection?
What are the CDC guidelines for reducing the risk of sexual transmission of Zika virus?
What are the FDA guidelines for reducing the risk of transmission of Zika virus via blood products?
What are the CDC recommendations for testing of Zika virus infection?
What are the CDC guidelines for the management of congenital Zika virus infection in infants?
What are the CDC guidelines on Zika infection testing during pregnancy?
What are the CDC recommendations regarding conception after exposure to Zika virus?
When is testing for Zika virus infection indicated?
How can a pregnant woman traveling to endemic areas minimize her risk of exposure to Zika virus?
When is Zika virus infection testing indicated in pregnant women?
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Rash in a patient with Zika virus infection. Courtesy of Carolina O Barbosa, MD, and Antonio C Bandeira, MD, Salvador, Brazil.
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Rash in a patient with Zika virus infection. Courtesy of Carolina O Barbosa, MD, and Antonio C Bandeira, MD, Salvador, Brazil.
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Rash in a patient with Zika virus infection. Courtesy of Carolina O Barbosa, MD, and Antonio C Bandeira, MD, Salvador, Brazil.
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Rash in a patient with Zika virus infection. Courtesy of Carolina O Barbosa, MD, and Antonio C Bandeira, MD, Salvador, Brazil.
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Laboratory-confirmed symptomatic Zika virus disease cases reported to ArboNET by states and territories - United States, 2017. Courtesy of the Centers for Disease Control and Prevention (CDC).
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World map of areas with color-coded risk for Zika based on current or previously reported Zika cases, as of November 4, 2019. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Diagnostic testing to interpret infection from Dengue and Zika virus. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Dengue and Zika virus diagnostic testing interpretation in nonpregnant and pregnant patients. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Testing algorithm for pregnant women with a clinically compatible illness and risk for Zika and Dengue virus. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Dengue and Zika virus testing recommendations for nonpregnant persons with a clinically compatible illness and risk for infection with both viruses. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Interpretation of results of laboratory testing of infant’s blood, urine, and/or cerebrospinal fluid for evidence of congenital Zika virus infection. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Recommendations for the evaluation of infants with possible congenital Zika virus infection based on infant clinical findings, maternal testing results, and infant testing results - United States, October 2017. Courtesy of the Centers for Disease Control and Prevention (CDC).
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Consultations for infants with clinical findings consistent with congenital Zika syndrome - United States, October 2017. Courtesy of the Centers for Disease Control and Prevention (CDC).