Overview
What is chronic glomerulonephritis?
How is chronic glomerulonephritis defined and classified?
What is the prognosis for chronic glomerulonephritis?
What is the pathophysiology of chronic glomerulonephritis?
What are the disease progression patterns of chronic glomerulonephritis?
What is the US prevalence of chronic glomerulonephritis?
What is the global prevalence of chronic glomerulonephritis?
What is included in patient education about chronic glomerulonephritis?
Presentation
What is the focus of the clinical history to evaluate for chronic glomerulonephritis?
Which physical exam findings are characteristic of chronic glomerulonephritis?
Which complications of chronic glomerulonephritis are indications for urgent dialysis?
DDX
What are the differential diagnoses for Chronic Glomerulonephritis?
Workup
What is the role of urinalysis in the workup for chronic glomerulonephritis?
How is urinary protein excretion determined during the workup for chronic glomerulonephritis?
What is the role of a CBC count in the workup for chronic glomerulonephritis?
What is the role of serum chemistry in the workup for chronic glomerulonephritis?
What is the role of renal ultrasonography in the workup for chronic glomerulonephritis?
What is the role of kidney biopsy in the workup for chronic glomerulonephritis?
Treatment
How is chronic glomerulonephritis treated?
How is blood pressure managed in chronic glomerulonephritis?
How is fibrosis inhibited in chronic glomerulonephritis?
What is the role of antioxidants in the treatment of chronic glomerulonephritis?
What is the role of sodium bicarbonate in the treatment of chronic glomerulonephritis?
What is the role of direct renin inhibitors in the treatment of chronic glomerulonephritis?
How is renal osteodystrophy managed in chronic glomerulonephritis?
How is hyperlipidemia managed in chronic glomerulonephritis?
Which specialist consultations are beneficial to patients with chronic glomerulonephritis?
Which dietary modifications are used in the treatment of chronic glomerulonephritis?
Which activity modifications are used in the treatment of chronic glomerulonephritis?
What is the impact of weight loss on the progression of chronic glomerulonephritis?
Medications
What is the role of medications in the treatment of chronic glomerulonephritis?
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Renal corpuscle.
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Photomicrograph of a kidney biopsy from a patient with crescentic glomerulonephritis showing prominent fibrocellular crescent formation and moderate mesangial proliferation in a glomerulus. Hematoxylin and eosin stain. Image courtesy of Wikipedia.
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Membranoproliferative glomerulonephritis (MPGN) type I. Glomerulus with lobular accentuation from increased mesangial cellularity. A segmental increase occurs in the mesangial matrix, and the peripheral capillary walls are thickened (hematoxylin and eosin stained section; original magnification × 250). Courtesy of John A. Minielly, MD.