Pinta Treatment & Management

Updated: Oct 29, 2019
  • Author: Nelson Ivan Agudelo Higuita, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Medical Care

The World Health Organization (WHO) recommends treatment of pinta with a single-dose intramuscular injection of long-acting benzathine penicillin (1.2 MU for adults; 0.6 MU for children). Penicillin render lesions noninfectious within 24 hours. [2]

Lesions become noninfectious within 24 hours of treatment.

Skin lesions heal slowly.

After treatment, nontreponemal titers should decline and can (but do not always) revert to negative.

The WHO has started a campaign to eradicate yaws (caused by T pallidum pertenue) by 2020 based on the mass treatment of endemic communities with an oral dose of azithromycin. T carateum is most likely sensitive to azithromycin, and this intervention could therefore have a concomitant effect on pinta in regions of Latin America where both yaws and pinta might still coexist. [2]


Surgical Care

Surgery has no role in pinta treatment.



Early pinta lesions usually improve with penicillin treatment, although the late changes of pinta are irreversible, often causing stigmatization in communities. [2]



Treatment of close contacts and household members is recommended to prevent the development of infection. [1]


Long-Term Monitoring

Long-term monitoring of pinta is unnecessary. Treatment resolves early lesions and, in persons with late infections, arrests progression. A fall in two or more dilutions in the nontreponemal tests may be seen after treatment with penicillin, but serology results might not revert to negative. [1]