Acalculous Cholecystitis Workup

Updated: Feb 14, 2019
  • Author: Homayoun Shojamanesh, MD; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Approach Considerations

It is crucial that clinicans rapidly identify cases of acute acalculous cholecystitis to avoid a delay in treatment and consequent clinical deterioration of affected patients. [2]

A complete blood cell (CBC) count, liver function studies, and blood culture tests are some of the main laboratory tests that should be performed. However, note that laboratory findings may be negative or inconclusive in late-stage disease, [2] and bile culture results are negative in nearly 50% of patients with acalculous cholecystitis, probably because of concurrent antibiotic therapy in these patients.

Perform abdominal ultrasonography [2] or computed tomography (CT) scanning.

For surgical candidates, perform cholecystectomy using an open or laparoscopic approach as indicated. For patients who are not surgical candidates, perform percutaneous cholecystostomy. [10, 11, 12, 13]