Endomyocardial Fibrosis Differential Diagnoses

Updated: Dec 29, 2020
  • Author: Ali A Sovari, MD, FACP, FACC; Chief Editor: Henry H Ooi, MD, MRCPI  more...
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Diagnostic Considerations

As with other forms of restrictive cardiomyopathy, distinguish endomyocardial fibrosis (EMF) from constrictive pericarditis.

Other conditions to consider in patients with suspected EMF include the following:

  • Anthracycline toxicity

  • Carcinoid heart disease

  • Drug-induced cardiotoxicity (eg, serotonin, methysergide, ergotamine, mercurial agents, busulfan)

  • Fabry disease

  • Fatty infiltration

  • Gaucher disease

  • Glycogen storage disease

  • Hurler disease

  • Idiopathic cardiomyopathy

  • Metastatic cancers

  • Radiation

  • Rheumatic heart disease

Occasionally, a masslike lesion seen in endomyocardial fibrosis masquerades as an intracardiac tumor.

Differential Diagnoses