Neuromodulation Surgery for Psychiatric Disorders Workup

Updated: Nov 17, 2021
  • Author: Jonathan P Miller, MD; Chief Editor: Brian H Kopell, MD  more...
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Laboratory Studies

Routine pre-surgical laboratory studies include a CBC and urinalysis to evaluate for evidence of infection, a coagulation panel to ensure normal clotting function, and a renal function panel prior to obtaining contrasted imaging studies to minimize the risks associated with administration of iodinated or gadolinium contrast media.


Imaging Studies

A volumetric, high-resolution MRI of the brain with and without intravenous gadolinium constrast is typically obtained as part of the pre-surgical evaluation prior to deep brain stimulation (DBS) implantation. Functional MRI may be obtained as part of a research protocol depending on institutional practices.


Other Tests

Neuropsychiatric testing to establish a pre-implantation baseline should be strongly considered for all potential deep brain stimulation (DBS) patients. This allows for assessment of any adverse effects of stimulation, and can also help assess for functional benefit of therapy. Particularly given the paucity of data surrounding DBS for psychiatric indications, this testing can be very useful from a research perspective.