Infantile Cortical Hyperostosis (Caffey Disease) Treatment & Management

Updated: Jan 26, 2021
  • Author: Cara Novick, MD; Chief Editor: Vinod K Panchbhavi, MD, FACS, FAOA, FABOS, FAAOS  more...
  • Print

Approach Considerations

No specific treatment exists for infantile cortical hyperostosis (Caffey disease). The disease is self-limited and usually resolves without sequelae. [30, 31] Some periods of exacerbation and remission may occur during the course of this condition.


Medical Care

Corticosteroids may be helpful in alleviating symptoms in severe cases, but these agents do not have any affect on the bone lesions. Nonsteroidal anti-inflammatory drugs (NSAIDs) may also be used to treat symptoms.