Anterior Ischemic Optic Neuropathy (AION) Medication

Updated: Feb 16, 2021
  • Author: Andrew A Dahl, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication Summary

Oral steroids are of little or no use in nonarteritic anterior ischemic optic neuropathy (NAION). Systemic steroids must be initiated early in the case of giant cell arteritis (GCA), especially if one eye is involved. Usually, the treatment prevents the second eye from becoming involved, but sometimes, vision is lost despite steroids. [20, 21, 22]  



Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, these agents modify the body's immune response to diverse stimuli. In those cases that overlap with the optic neuritis (inflammatory, demyelinating) group (ie, patients in their fourth to fifth decade), a trial of steroids (intravenous) is useful.

Methylprednisolone (Solu-Medrol, Depo-Medrol)

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.