Amblyopia Workup

Updated: Jul 20, 2018
  • Author: Kimberly G Yen, MD; Chief Editor: Hampton Roy, Sr, MD  more...
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Imaging Studies

If suspicion exists of an organic cause for decreased vision and the ocular examination is normal, then further investigations into retinal or optic nerve causes should be initiated. Studies to perform include imaging of the visual system through CT scan, MRI, and fluorescein angiography to assess the retina.


Other Tests

Although differences in the electrophysiologic responses of normal eyes versus amblyopic eyes have been reported, these techniques remain investigational and the differences are controversial.

Differences have been found using B-scans between the foveal structure of amblyopes compared to those without amblyopia. The differences found include an increase in the foveal thickness of amblyopic eyes along with a reduced foveal pit in the horizontal, but not vertical, meridian. [3]



See Physical.


Histologic Findings

Histologic studies of the lateral geniculate nucleus in kittens with deprivation amblyopia have shown that cells receiving input from the deprived eye were shrunken and atrophied, while cells receiving input from the nondeprived eye were expanded.