Canalicular Laceration Medication

Updated: May 05, 2018
  • Author: Christian El-Hadad, MD, CM, FRCSC; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication Summary

The medications used in treating canalicular lacerations are antibiotics that help to prevent infection. Intraoperatively, the wounds are decontaminated with copious irrigation of antibiotic solution. Postoperatively, topical antibiotic ointment is applied to the skin wound, topical antibiotic solution is instilled to treat the lacrimal system, and system antibiotics are used if wound contamination is possible. An ophthalmic antibiotic steroid often is used for topical use since it also decreases inflammation.



Class Summary

Used in prevention of postoperative infection, inflammation, and scarring of the lacrimal drainage system.

Dexamethasone/tobramycin (TobraDex)

Indicated for infections of the eye. Tobramycin interferes with bacterial protein synthesis by binding to 30S and 50S ribosomal subunits, which results in a defective bacterial cell membrane. Dexamethasone decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reducing capillary permeability.

Cephalexin (Keflex, Biocef, Keftab)

Indicated for infections. First-generation cephalosporin arrests bacterial growth by inhibiting bacterial cell wall synthesis. Bactericidal activity against rapidly growing organisms. Primary activity against skin flora; used for skin infections or prophylaxis in minor procedures.