Intraocular Tumors and Glaucoma Workup

Updated: Jun 25, 2020
  • Author: Andrew A Dahl, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Imaging Studies

Differentiation between benign and malignant processes of the choroid can be assisted by MRI and ultrasound evaluation.



For tissue diagnosis, fine-needle biopsy, aqueous aspiration, or excisional biopsy is needed.

Diagnosis of iris nevus is aided by fluorescein angiography of iris, aqueous aspiration, or biopsy.


Histologic Findings

Pigmented lesions: Melanoma consists of varying proportions of spindle cells and epithelioid cells, with the latter cell types associated with higher malignant potential. Reports indicate a 17% incidence of glaucoma in ciliary body melanoma, 7% in iris melanoma, and 2% in choroidal melanoma. The predominant mechanism also varies with tumor location.