Organic Solvent Neurotoxicity Follow-up

Updated: Dec 11, 2018
  • Author: Jonathan S Rutchik, MD, MPH, FACOEM; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Further Outpatient Care

See the list below:

  • Examinations and neurophysiologic and neuropsychological testing should be repeated 9 months to 1 year after the exposure is reduced or ceased.

  • Neuropsychological testing results generally stay the same or improve with time, though some authors (eg, Seppalainen) have reported that a substantial percentage worsen over time.



See the list below:

  • Exposure is prevented with appropriate use of PPE for those who work with organic solvents.

    • Industrial hygienists are vital members of any company occupational health and safety department.

    • Engineering controls are further steps that can be taken to decrease exposure. Choosing a less-toxic chemical as an alternative to in process, increasing ventilation, and adjusting shifts so that workers are exposed to toxins for less time than before are some engineering controls.

  • Environmental exposure may be reduced by means of community education, which may lead to local, state, and national regulation and increased policing. Education may also improve epidemiologic research, which may prove or disprove the relationship between exposure to a solvent and health consequences.