Nutritional Neuropathy Medication

Updated: Oct 28, 2022
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Nicholas Lorenzo, MD, CPE, MHCM, FAAPL  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and prevent complications.



Class Summary

To treat a nutritional neuropathy, replacing the deficient nutrients is necessary. This may involve administration of folate, thiamine (vitamin B 1 ), nicotinamide, pyridoxine (vitamin B 6 ), cyanocobalamin (vitamin B 12 ), alpha-tocopherol (vitamin E), vitamin A, or protein.

Thiamine (Thiamilate)

For thiamine deficiency syndromes.

Niacin (Vitamin B 3 )

Source of niacin used in tissue respiration, lipid metabolism, and glycogenolysis.

Cyanocobalamin (Crystamine)

Deoxyadenosylcobalamin and hydroxocobalamin are active forms of vitamin B 12 in humans. Vitamin B 12 synthesized by microbes but not humans or plants. Vitamin B 12 deficiency may result from intrinsic factor deficiency (pernicious anemia), partial or total gastrectomy, or diseases of distal ileum.

Folate (Folvite)

Important cofactor for enzymes used to produce RBCs.

Alpha-tocopherol (Vita-Plus E Softgels, Vitec, Aquasol E)

Protects polyunsaturated fatty acids in membranes from attack by free radicals and protects RBCs against hemolysis.

Multivitamins (MVI-12, Cernevit-12)

Dietary supplement.