Progressive Supranuclear Palsy Questions & Answers

Updated: Oct 17, 2018
  • Author: Eric R Eggenberger, DO, MS, FAAN; Chief Editor: Selim R Benbadis, MD  more...
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Questions & Answers

Overview

How is progressive supranuclear palsy (PSP) characterized?

What are the signs and symptoms of progressive supranuclear palsy (PSP)?

Which physical findings suggest progressive supranuclear palsy (PSP)?

What are the visual signs and symptoms of progressive supranuclear palsy (PSP)?

What are the cognitive signs and symptoms of progressive supranuclear palsy (PSP)?

What are the diagnostic criteria for progressive supranuclear palsy (PSP)?

What is the role of MRI in the diagnosis of progressive supranuclear palsy (PSP)?

What is the role of sleep studies in the diagnosis of progressive supranuclear palsy (PSP)?

How is progressive supranuclear palsy (PSP) treated?

What is progressive supranuclear palsy (PSP)?

What is the pathophysiology of progressive supranuclear palsy (PSP)?

What causes progressive supranuclear palsy (PSP)?

What causes progressive supranuclear palsy (PSP)?

What is the prevalence of progressive supranuclear palsy (PSP) in the US?

What is the global prevalence of progressive supranuclear palsy (PSP)?

Which patient groups have the highest prevalence of progressive supranuclear palsy (PSP)?

What is the prognosis of progressive supranuclear palsy (PSP)?

What is included in patient education about progressive supranuclear palsy (PSP)?

Presentation

Which clinical history findings are characteristic of progressive supranuclear palsy (PSP)?

What are the cardinal manifestations of progressive supranuclear palsy (PSP)?

What are the prominent features of progressive supranuclear palsy (PSP)?

What is the focus of the physical exam to evaluate progressive supranuclear palsy (PSP)?

Which motor findings are characteristic of progressive supranuclear palsy (PSP)?

Which cranial nerve exam findings are characteristic of progressive supranuclear palsy (PSP)?

How is progressive supranuclear palsy (PSP) differentiated from Alzheimer disease?

What is the accuracy of clinical diagnostic criteria for progressive supranuclear palsy (PSP)?

What are the National Institute of Neurological Disorders and Stroke (NINDS)/Society for PSP diagnostic criteria for progressive supranuclear palsy (PSP)?

What is the accuracy of the National Institute of Neurological Disorders and Stroke (NINDS)/Society for PSP diagnostic criteria for progressive supranuclear palsy (PSP)?

What are the primary complications of progressive supranuclear palsy (PSP)?

DDX

How is progressive supranuclear palsy (PSP) diagnosed?

Which conditions should be included in the differential diagnosis of progressive supranuclear palsy (PSP)?

What are the differential diagnoses for Progressive Supranuclear Palsy?

Workup

What is the role of lab testing in the diagnosis of progressive supranuclear palsy (PSP)?

Which MRI findings are characteristic of advanced progressive supranuclear palsy (PSP)?

What is the role of neuroimaging studies in the diagnosis of progressive supranuclear palsy (PSP)?

Which findings on polysomnography are characteristic of progressive supranuclear palsy (PSP)?

Which histologic findings are characteristic of progressive supranuclear palsy (PSP)?

Treatment

Which medications are used in the treatment of progressive supranuclear palsy (PSP)?

What is the role of ECT in the treatment of progressive supranuclear palsy (PSP)?

What is the role of pharmacologic therapy in the treatment of progressive supranuclear palsy (PSP)?

Which specialist consultations are beneficial to patients with progressive supranuclear palsy (PSP)?

Which dietary and activity modifications are used in the treatment of progressive supranuclear palsy (PSP)?

What is included in long-term monitoring of patients with progressive supranuclear palsy (PSP)?

Medications

What is the role of dopamine in the treatment of progressive supranuclear palsy (PSP)?

Which medications in the drug class Tricyclic Antidepressants, TCAs are used in the treatment of Progressive Supranuclear Palsy?

Which medications in the drug class Antiparkinson/dopamine agonists are used in the treatment of Progressive Supranuclear Palsy?