Huntington Disease Questions & Answers

Updated: Feb 27, 2019
  • Author: Fredy J Revilla, MD, FAAN, FANA; Chief Editor: Selim R Benbadis, MD  more...
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Questions & Answers

Overview

What is Huntington disease (HD)?

What are the findings of the TRACK-HD study on Huntington disease (HD)?

Where does the neuropathology in Huntington disease (HD) occur?

What are the stages of Huntington disease (HD)?

What are the genetics of Huntington disease (HD)?

What is the role of neuronal intranuclear inclusions (NIIs) in the development of Huntington disease (HD)?

What causes Huntington disease (HD)?

What is the role of excitotoxicity in the development of Huntington disease (HD)?

What is the role of oxidative stress in the development of Huntington disease (HD)?

What is the role of impaired energy metabolism in the development of Huntington disease (HD)?

What is the role of apoptosis in the development of Huntington disease (HD)?

What is the prevalence of Huntington disease (HD) in the US?

What is the international prevalence of Huntington disease (HD)?

What are age-related demographics of Huntington disease (HD)?

What is the prognosis of Huntington disease (HD)?

What information should be provided to patients about Huntington disease (HD)?

Presentation

What is the clinical history of Huntington disease (HD)?

What are the traits of dementia syndrome in Huntington disease (HD)?

What are physical findings in Huntington disease (HD)?

DDX

What are the differential diagnoses for Huntington Disease?

Workup

What are the approach considerations in the workup of Huntington disease (HD)?

What is the staging system for Huntington disease (HD)?

Treatment

Which surgical procedures are indicated in the treatment of Huntington disease (HD)?

What is the treatment approach in Huntington disease (HD)?

How is depression treated in patients with Huntington disease (HD)?

Guidelines

What are the guidelines for treating neuropsychiatric symptoms of Huntington disease (HD)?

Medications

Which medications are indicated in the treatment of Huntington disease (HD)?

Which medications in the drug class Antidepressants are used in the treatment of Huntington Disease?

Which medications in the drug class Antipsychotic agents are used in the treatment of Huntington Disease?

Which medications in the drug class Anticonvulsant are used in the treatment of Huntington Disease?

Which medications in the drug class Monoamine Inhibitors are used in the treatment of Huntington Disease?