Closure of Complicated Wounds Workup

Updated: Nov 05, 2021
  • Author: Mark S Granick, MD, FACS; Chief Editor: William D James, MD  more...
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Laboratory Studies

Laboratory studies are not required in the vast majority of wound closure settings, but in cases of complex wounds or chronic/nonhealing wounds, they may aid the surgeon in tailoring treatment. Nutrition laboratory studies, including albumin, prealbumin, and transferrin levels, can indicate if the patient is appropriately nourished and able to heal the wound. Zinc or iron deficiencies, along with other mineral deficiencies, can prolong or inhibit the wound healing process altogether. Similarly, deficiencies in vitamin C, D, and other key vitamins can prevent a patient's wounds from properly healing. In select patients, a preoperative nutritional workup may be warranted.