Monilethrix Differential Diagnoses

Updated: Jun 06, 2022
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Diagnostic Considerations

Also consider pili torti, trichorrhexis nodosa, and pseudomonilethrix.

Trichoscopy performed with a handheld dermoscope or a videodermoscope may be useful in distinguishing monilethrix from other scalp disorders. [26]

Hypotrichosis in one family was evaluated, with some members having monilethrixlike scalp hair. A novel deletion mutation in the DSG4 gene underlies autosomal recessive hypotrichosis with variable phenotype. [27] Thus, mutations in the DSG4 gene may result in both hypotrichosis and monilethrixlike scalp hair.

Differential Diagnoses