Winchester Syndrome Treatment & Management

Updated: Apr 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
  • Print
Treatment

Medical Care

To establish the final diagnosis of Winchester syndrome (WS), patients with findings suggestive of this pathologic syndrome should undergo examination by many specialists (see Consultations). Pamidronate does not improve peripheral osteolysis in multicentric osteolysis and nodular arthropathy caused by a mutation in the matrix metalloproteinase 2 gene. [38]

Next:

Consultations

To establish the final diagnosis and to plan further medical care, patients with findings suggestive of this pathologic syndrome require examinations by specialists, including a pediatrician, a radiologist, a rheumatologist, an orthopedist, an ophthalmologist, a neurologist, a dermatologist, a stomatologist, and a psychologist.

Families with this syndrome should be referred for adequate genetic counseling and consultations.

Previous
Next:

Activity

The activity of patients is limited because of the pathologic changes that occur in the joints of the limbs and in the backbone.

Previous
Next:

Long-Term Monitoring

Physiotherapy is advised. Some individuals with Winchester syndrome require orthopedic equipment.

Previous