Mammary Paget Disease Medication

Updated: Apr 07, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and prevent complications. A Cochrane review of aminolevulinic acid photodynamic therapy for mammary and extramammary Paget disease identified 21 retrospective and two prospective noncomparative studies with a total of 99 patients. The results suggest that this modality might be considered as adjunctive therapy for selected patients. [41]


Topical Skin Products

Class Summary

These agents provide a photodynamic treatment for low-risk malignant cells and may improve morbidity.

Aminolevulinic acid (Levulan Kerastick)

Aminolevulinic acid is a metabolic precursor of the photosensitizer protoporphyrin lX. When exposed to light of appropriate wavelength and energy, it induces local cytotoxicity through a photodynamic reaction.