Dermatologic Manifestations of Pellagra Medication

Updated: May 13, 2022
  • Author: Vladimir Hegyi, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
  • Print


Class Summary

Exogenous administration cures the syndrome and, within the levels prescribed, niacin use is not associated with the uncomfortable flushing observed in other conditions (eg, hypercholesterolemia). Niacinamide (nicotinamide) is usually tolerated better than nicotinic acid, and it is the preferred agent because it does not precipitate the flushing, itching, and burning observed after the ingestion of large doses of niacin.

Niacin (Vitamin B-3)

Niacin is used in tissue respiration, lipid metabolism, and glycogenolysis.