Generalized Essential Telangiectasia Differential Diagnoses

Updated: Dec 15, 2017
  • Author: David Green, MD, PA; Chief Editor: Dirk M Elston, MD  more...
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Diagnostic Considerations

Generalized essential telangiectasia is distinguished from other diseases, such as hereditary hemorrhagic telangiectasia, by the apparent absence of any preceding or coexisting cutaneous or systemic disease. [15]

No visceral involvement and no hemorrhagic tendency are noted, although one report describes a patient with generalized essential telangiectasia and gastrointestinal tract bleeding resulting from the presence of a watermelon stomach. [16]

Conjunctival telangiectases are uncommon in generalized essential telangiectasia but have been reported. [9, 10, 11, 12, 13]

The telangiectatic form of mastocytosis known as telangiectasia macularis eruptiva perstans manifests as telangiectases overlying brown macules that may be generalized in distribution.

Although angiokeratomas of Fabry disease are usually papular, they have been observed as flat and may resemble the speckled appearance of the discrete red macules sometimes seen in generalized essential telangiectasia.

Differential Diagnoses