Traumatic Ulcers Workup

Updated: Oct 09, 2017
  • Author: Glen Houston, DDS, MSD; Chief Editor: Jeff Burgess, DDS, MSD  more...
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See the list below:

  • Ulcerations without an etiology or those that persist despite therapy may need to be examined microscopically to exclude malignancy and other causes.

  • Some ulcers caused by trauma may resemble squamous cell carcinoma [12] or granulomatous ulcers (eg, those resulting from deep fungal infections or tuberculosis). If the cause of the ulceration is not obvious at clinical examination or if no response to local therapy is noted, biopsy may be indicated to exclude these conditions. Also see Oral Manifestations of Systemic Diseases.


Histologic Findings

Microscopic features include an area of surface ulceration covered by a fibrinopurulent membrane consisting of acute inflammatory cells intermixed with fibrin. The stratified squamous epithelium from the adjacent surface may be hyperplastic and exhibit areas of reactive squamous atypia. The ulcer bed is composed of a proliferation of granulation tissue with areas of edema and an infiltrate of acute and chronic inflammatory cells.