Nevus Sebaceus Differential Diagnoses

Updated: Oct 14, 2021
  • Author: Anwar Al Hammadi, MD, FRCPC; Chief Editor: William D James, MD  more...
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Diagnostic Considerations

In early infancy, lesions in the scalp must be distinguished from cutis aplasia, which has a smoother papyraceous surface.

Nevus syringocystadenomatosus papilliferus may be difficult to distinguish at clinical examination, although the surface tends to be pink and nodular rather than yellow and velvety.

Early juvenile xanthogranulomas may be similar in their clinical appearance, although these generally develop rapidly into distinctive domed, papular, or nodular lesions.

Solitary mastocytomas may also be confused at clinical examination during infancy. Histologic examination clearly identifies all the disorders previously mentioned.

Congenital triangular alopecia should also be differentiated during infancy and childhood.

Differential Diagnoses