Diagnostic Considerations
In early infancy, lesions in the scalp must be distinguished from cutis aplasia, which has a smoother papyraceous surface.
Nevus syringocystadenomatosus papilliferus may be difficult to distinguish at clinical examination, although the surface tends to be pink and nodular rather than yellow and velvety.
Early juvenile xanthogranulomas may be similar in their clinical appearance, although these generally develop rapidly into distinctive domed, papular, or nodular lesions.
Solitary mastocytomas may also be confused at clinical examination during infancy. Histologic examination clearly identifies all the disorders previously mentioned.
Congenital triangular alopecia should also be differentiated during infancy and childhood.
Differential Diagnoses
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Nevus sebaceus in a 4-month-old baby manifesting as nodular plaque.
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Brownish wartlike plaque in a 25-year-old patient.
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Nevus sebaceus manifesting as a bald patch in a child.
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Nevus sebaceus manifesting as an orange-yellow plaque with a smooth or somewhat velvety surface in a 6-month-old baby.
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Nevus sebaceus manifesting as a small plaque beside a scaly scalp in a 13-year-old boy.
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Linear type of nevus sebaceus.
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Mild papillomatosis of the epidermis with sebaceus gland lobules opening directly onto the epidermis.
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Mild papillomatosis at high power.
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Verrucous plaque in a 19-year-old woman.
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Verrucous plaque in a 12-year-old-girl.