Cylindroma Treatment & Management

Updated: Nov 08, 2019
  • Author: Angela (Angel) M Crotty, MD; Chief Editor: Dirk M Elston, MD  more...
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Surgical Care

For solitary lesions, the treatment of choice is surgical excision. [51] Other treatments include electrodesiccation/curettage and cryotherapy.

For small cylindromas, the carbon dioxide laser may be used. [52] Retamar et al used carbon dioxide laser to treat facial trichoepitheliomas in two patients, with good results. [53]

Multiple cylindromas usually require extensive plastic surgery that may be obviated by progressively excising a group of nodules in multiple procedures. [54]


Medical Care

Inhibition of NF-κB signalling shows potential to be a therapeutic option outside of surgery for patients with CYLD cutaneous syndrome. Models of TRK signal inhibition almost showed some potential for CYLD-mutation neoplasms. [11]


Long-Term Monitoring

Follow-up care of patients with multiple cylindromas is recommended because of the tendency for new lesions to develop. Follow-up care is also recommended because of the risk of malignant degeneration.