Atypical Fibroxanthoma Treatment & Management

Updated: Oct 14, 2020
  • Author: Forrest C Brown, MD; Chief Editor: William D James, MD  more...
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Surgical Care

In the past, many lesions were diagnosed clinically as pyogenic granuloma and removed by shave and curettage, without recurrence, which has prompted physicians to treat atypical fibroxanthoma (AFX) conservatively. Local recurrence and spread to lymph nodes may occur. [14, 15] This suggests that complete tumor removal is required. Simple excision with a margin of normal skin or Mohs micrographic surgery may be appropriate.

Mohs micrographic surgery, with its high reliability of complete tumor removal and tissue-conserving property, is an excellent choice for AFX on the head and neck. [16, 17, 18, 19, 20, 21]



Instruct patients to avoid excessive sun exposure.