Pyoderma Vegetans Clinical Presentation

Updated: Mar 26, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
  • Print


Some patients with pyoderma vegetans (PV) may have a history of hidradenitis suppurativa. [20, 21] This rare inflammatory dermatosis may involve skin and mucosa with pustular and vesicular plaques. In some patients, vegetating plaques may appear in the axillary, vulvar, and inguinal areas. [22] Disfiguring facial pyoderma vegetans has been described. [23]


Physical Examination

Both clinical and histologic findings are necessary to make the diagnosis of pyoderma vegetans. The plaques are often multiple; some may appear purulent, others hyperkeratotic. [24] At clinical examination, multiple pustules and large verrucous plaques with an elevated border are identified (note the images below). It may rarely appear on the penis. [25] At histologic examination, pseudoepitheliomatous hyperplasia is demonstrated.

A 24-year-old woman with rapidly evolving pyoderma A 24-year-old woman with rapidly evolving pyoderma vegetans.
Pyoderma vegetans. Pyoderma vegetans.