Dermatologic Manifestations of Lymphogranuloma Venereum Differential Diagnoses

Updated: May 10, 2018
  • Author: Jose A Plaza, MD; Chief Editor: Dirk M Elston, MD  more...
  • Print

Diagnostic Considerations

The diagnosis of lymphogranuloma venereum (LGV) should not preclude a thorough search for other sexually transmitted diseases (STDs) (eg, granuloma inguinale, syphilis, chancroid) that may be cured by different treatment modalities. The use of broad-spectrum antibiotics to replace an accurate differential diagnosis and focused treatment should be discouraged.

The diagnosis of LGV may be missed easily in women and homosexual males because they tend not to present with the classic inguinal lymphadenopathy. Careful diagnostic consideration should be used in these patient populations.

Primary lesion considerations include the following:

  • Genital herpes
  • Primary syphilis
  • Chancroid
  • Genitoanorectal syndrome
  • Rectal strictures resulting from carcinoma

Differential Diagnoses