Acquired Angioedema Due to C1 Inhibitor Deficiency Treatment & Management

Updated: May 20, 2020
  • Author: Amanda T Moon, MD; Chief Editor: William D James, MD  more...
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Treatment

Approach Considerations

A variety of agents can be used for acute attacks of acquired angioedema (see Medication). [13] Depending on the symptoms and the site of the angioedema, intensive support may be necessary, including intravenous fluids. Intubation may be necessary in cases of laryngeal edema.

When possible, the underlying disorder should be treated. The resolution of angioedema has been reported with the treatment of underlying disease, although recurrences have occurred despite appropriate treatment of the disorder. In acquired angioedema type I (AAE-I), treatment of the associated lymphoproliferative process may result in correction of the abnormality.

Nonmyeloablative stem cell transplantation resulted in sustained remission in a patient with previously refractory acquired angioedema type I. [14]

Go to Angioedema, Pediatric Angioedema, Acute Angioedema, and Hereditary Angioedema for complete information on this topic.