Pediatric Sjogren Syndrome Differential Diagnoses

Updated: Sep 09, 2021
  • Author: Marietta Morales De Guzman, MD; Chief Editor: Lawrence K Jung, MD  more...
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DDx

Diagnostic Considerations

Conditions to consider in the differential diagnosis of Sjögren syndrome include the following:

  • Medications that cause sicca symptoms (anticholinergic agents)
  • Recurrent juvenile parotitis
  • Oropharyngeal candidiasis
  • Gingivitis/periodontitis
  • Retrograde bacterial sialadenitis
  • Halitosis
  • Superficial mucoceles
  • Compromised nutrition
  • Dryness of the nasal and vaginal mucosa and skin
  • Pregnancy complications due to autoantibodies
  • Mumps
  • Sarcoidosis
  • SLE 
  • Mixed connective tissue disease
  • Systemic sclerosis 
  • IgG 4 disease
  • Hepatitis C

Differentials

Anorexia Nervosa

Infections in the Immunocompromised Host

Lymphoproliferative Disorders

Pediatric Bulimia

Pediatric Graft Versus Host Disease

Pediatric HIV Infection

Pediatric Herpes Simplex Virus Infection

Pediatric Mononucleosis and Epstein-Barr Virus Infection

Vasculitis and Thrombophlebitis

Differential Diagnoses