Pediatric Costochondritis Medication

Updated: Aug 20, 2018
  • Author: Joseph P Garry, MD, FACSM, FAAFP; Chief Editor: Lawrence K Jung, MD  more...
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Medication Summary

NSAIDs provide analgesia for mild-to-moderate chest pain and may modulate the presumed inflammatory process. Purely analgesic drugs (eg, acetaminophen, tramadol hydrochloride) may suffice.


Nonsteroidal anti-inflammatory drugs

Class Summary

These provide analgesia and may play a role in controlling inflammation.

Ibuprofen (Motrin, Advil, Ibuprin)

Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Naproxen (Aleve)

Available as OTC preparation and in prescription form; OTC preparation has faster onset of action, though limited duration of action. Prescription form is available in both pill and elixir forms and has a convenient bid-dosing schedule.



Class Summary

These may be used to relieve mild-to-moderate pain.

Acetaminophen (Tylenol)

May be used to relieve mild-to-moderate pain. Inhibits prostaglandin synthetase in the CNS by inhibiting cyclooxygenase.

Tramadol hydrochloride (Ultram)

Inhibits ascending pain pathways, altering perception of and response to pain. Also inhibits reuptake of norepinephrine and serotonin.