Cystic Adenomatoid Malformation Differential Diagnoses

1. Wilson RD, Hedrick HL, Liechty KW, et al. Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatment. Am J Med Genet A. 2006 Jan 15. 140(2):151-5. [QxMD MEDLINE Link].

2. Kotecha S, Barbato A, Bush A, Claus F, Davenport M, Delacourt C, et al. Antenatal and postnatal management of congenital cystic adenomatoid malformation. Paediatr Respir Rev. 2012 Sep. 13(3):162-70; quiz 170-1. [QxMD MEDLINE Link].

3. Adzick NS, Harrison MR, Crombleholme TM, et al. Fetal lung lesions: management and outcome. Am J Obstet Gynecol. 1998 Oct. 179(4):884-9. [QxMD MEDLINE Link].

4. Adzick NS. Management of fetal lung lesions. Clin Perinatol. 2003 Sep. 30(3):481-92. [QxMD MEDLINE Link].

5. Luján M, Bosque M, Mirapeix RM, Marco MT, Asensio O, Domingo C. Late-onset congenital cystic adenomatoid malformation of the lung. Embryology, clinical symptomatology, diagnostic procedures, therapeutic approach and clinical follow-up. Respiration. 2002. 69(2):148-54. [QxMD MEDLINE Link].

6. Sauvat F, Michel JL, Benachi A, Emond S, Revillon Y. Management of asymptomatic neonatal cystic adenomatoid malformations. J Pediatr Surg. 2003 Apr. 38(4):548-52. [QxMD MEDLINE Link].

7. Laberge JM, Flageole H, Pugash D, et al. Outcome of the prenatally diagnosed congenital cystic adenomatoid lung malformation: a Canadian experience. Fetal Diagn Ther. 2001 May-Jun. 16(3):178-86. [QxMD MEDLINE Link].

8. Duncombe GJ, Dickinson JE, Kikiros CS. Prenatal diagnosis and management of congenital cystic adenomatoid malformation of the lung. Am J Obstet Gynecol. 2002 Oct. 187(4):950-4. [QxMD MEDLINE Link].

9. Parikh D, Samuel M. Congenital cystic lung lesions: is surgical resection essential?. Pediatr Pulmonol. 2005 Dec. 40(6):533-7. [QxMD MEDLINE Link].

10. Métivier AC, Denoux Y, Tcherakian C, Puyo P, Rivaud E, Mellot F, et al. [Pulmonary cystic adenomatoid malformation in an adult patient: an underdiagnosed disease]. Rev Pneumol Clin. 2011 Sep. 67(4):275-80. [QxMD MEDLINE Link].

11. Crombleholme TM, Coleman B, Hedrick H, et al. Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung. J Pediatr Surg. 2002 Mar. 37(3):331-8. [QxMD MEDLINE Link].

12. Kamata S, Ishikawa S, Usui N, et al. Clinical significance of the lung/thorax transverse-area ratio in fetuses with cystic lung disease. Pediatr Surg Int. 1999. 15(7):470-4. [QxMD MEDLINE Link].

13. Shanmugam G, MacArthur K, Pollock JC. Congenital lung malformations--antenatal and postnatal evaluation and management. Eur J Cardiothorac Surg. 2005 Jan. 27(1):45-52. [QxMD MEDLINE Link].

14. Stanton M, Njere I, Ade-Ajayi N, Patel S, Davenport M. Systematic review and meta-analysis of the postnatal management of congenital cystic lung lesions. J Pediatr Surg. 2009 May. 44(5):1027-33. [QxMD MEDLINE Link].

15. Wong A, Vieten D, Singh S, Harvey JG, Holland AJ. Long-term outcome of asymptomatic patients with congenital cystic adenomatoid malformation. Pediatr Surg Int. 2009 Jun. 25(6):479-85. [QxMD MEDLINE Link].

16. Stocker JT, Madewell JE, Drake RM. Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. Hum Pathol. 1977 Mar. 8(2):155-71. [QxMD MEDLINE Link].

17. Usui N, Kamata S, Sawai T, et al. Outcome predictors for infants with cystic lung disease. J Pediatr Surg. 2004 Apr. 39(4):603-6. [QxMD MEDLINE Link].

18. Murphy JJ, Blair GK, Fraser GC, et al. Rhabdomyosarcoma arising within congenital pulmonary cysts: report of three cases. J Pediatr Surg. 1992 Oct. 27(10):1364-7. [QxMD MEDLINE Link].

19. Granata C, Gambini C, Balducci T, Toma P, Michelazzi A, Conte M. Bronchioloalveolar carcinoma arising in congenital cystic adenomatoid malformation in a child: a case report and review on malignancies originating in congenital cystic adenomatoid malformation. Pediatr Pulmonol. 1998 Jan. 25(1):62-6. [QxMD MEDLINE Link].

20. Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake AW. Increased cell proliferation and decreased apoptosis characterize congenital cystic adenomatoid malformation of the lung. J Pediatr Surg. 1998 Jul. 33(7):1043-6; discussion 1047. [QxMD MEDLINE Link].

21. Liechty KW, Crombleholme TM, Quinn TM, Cass DL, Flake AW, Adzick NS. Elevated platelet-derived growth factor-B in congenital cystic adenomatoid malformations requiring fetal resection. J Pediatr Surg. 1999 May. 34(5):805-9; discussion 809-10. [QxMD MEDLINE Link].

22. Volpe MV, Pham L, Lessin M, et al. Expression of Hoxb-5 during human lung development and in congenital lung malformations. Birth Defects Res A Clin Mol Teratol. 2003 Aug. 67(8):550-6. [QxMD MEDLINE Link].

23. Wang X, Wolgemuth DJ, Baxi LV. Overexpression of HOXB5, cyclin D1 and PCNA in congenital cystic adenomatoid malformation. Fetal Diagn Ther. 2011. 29(4):315-20. [QxMD MEDLINE Link].

24. Schwartz DS, Reyes-Mugica M, Keller MS. Imaging of surgical diseases of the newborn chest. Intrapleural mass lesions. Radiol Clin North Am. 1999 Nov. 37(6):1067-78, v. [QxMD MEDLINE Link].

25. Hernanz-Schulman M. Cysts and cystlike lesions of the lung. Radiol Clin North Am. 1993 May. 31(3):631-49. [QxMD MEDLINE Link].

26. Kim WS, Lee KS, Kim IO, et al. Congenital cystic adenomatoid malformation of the lung: CT-pathologic correlation. AJR Am J Roentgenol. 1997 Jan. 168(1):47-53. [QxMD MEDLINE Link].

27. Adzick NS, Harrison MR. Management of the fetus with a cystic adenomatoid malformation. World J Surg. 1993 May-Jun. 17(3):342-9. [QxMD MEDLINE Link].

28. Hubbard AM, Harty P. Prenatal magnetic resonance imaging of fetal anomalies. Semin Roentgenol. 1999 Jan. 34(1):41-7. [QxMD MEDLINE Link].

29. Hubbard AM, Harty MP, States LJ. A new tool for prenatal diagnosis: ultrafast fetal MRI. Semin Perinatol. 1999 Dec. 23(6):437-47. [QxMD MEDLINE Link].

30. Quercia M, Panza R, Calderoni G, Di Mauro A, Laforgia N. Lung ultrasound: a new tool in the management of congenital lung malformation. Am J Perinatol. 2019 Jul. 36 (S 02):S99-S105. [QxMD MEDLINE Link].

31. Stocker JT. Cystic lung disease in infants and children. Fetal Pediatr Pathol. 2009. 28(4):155-84. [QxMD MEDLINE Link].

32. Barikbin P, Roehr CC, Wilitzki S, Kalache K, Degenhardt P, Bührer C, et al. Postnatal lung function in congenital cystic adenomatoid malformation of the lung. Ann Thorac Surg. 2015 Apr. 99 (4):1164-9. [QxMD MEDLINE Link].

33. Makhija Z, Moir CR, Allen MS, Cassivi SD, Deschamps C, Nichols FC 3rd, et al. Surgical management of congenital cystic lung malformations in older patients. Ann Thorac Surg. 2011 May. 91(5):1568-73; discussion 1573. [QxMD MEDLINE Link].

34. Frenckner B, Freyschuss U. Pulmonary function after lobectomy for congenital lobar emphysema and congenital cystic adenomatoid malformation. A follow-up study. Scand J Thorac Cardiovasc Surg. 1982. 16(3):293-8. [QxMD MEDLINE Link].

35. Hijkoop A, van Schoonhoven MM, van Rosmalen J, et al. Lung function, exercise tolerance, and physical growth of children with congenital lung malformations at 8 years of age. Pediatr Pulmonol. 2019 Aug. 54 (8):1326-34. [QxMD MEDLINE Link].

36. Asabe K, Oka Y, Shirakusa T. Fetal case of congenital cystic adenomatoid malformation of the lung: fetal therapy and a review of the published reports in Japan. Congenit Anom (Kyoto). 2005 Sep. 45(3):96-101. [QxMD MEDLINE Link].

37. Bunduki V, Ruano R, da Silva MM, et al. Prognostic factors associated with congenital cystic adenomatoid malformation of the lung. Prenat Diagn. 2000 Jun. 20(6):459-64. [QxMD MEDLINE Link].

38. Calvert JK, Boyd PA, Chamberlain PC, Syed S, Lakhoo K. Outcome of antenatally suspected congenital cystic adenomatoid malformation of the lung: 10 years' experience 1991-2001. Arch Dis Child Fetal Neonatal Ed. 2006 Jan. 91(1):F26-8. [QxMD MEDLINE Link].

39. Ierullo AM, Ganapathy R, Crowley S, et al. Neonatal outcome of antenatally diagnosed congenital cystic adenomatoid malformations. Ultrasound Obstet Gynecol. 2005 Aug. 26(2):150-3. [QxMD MEDLINE Link].

40. Ioachimescu OC, Mehta AC. From cystic pulmonary airway malformation, to bronchioloalveolar carcinoma and adenocarcinoma of the lung. Eur Respir J. 2005 Dec. 26(6):1181-7. [QxMD MEDLINE Link].

41. Kulwa E, Tharakan T, Baxi L. Congenital cystic adenomatoid malformation in the fetus: a hypothesis of its development. Fetal Diagn Ther. 2005 Sep-Oct. 20(5):472-4. [QxMD MEDLINE Link].

42. Tawil MI, Pilling DW. Congenital cystic adenomatoid malformation: is there a difference between the antenatally and postnatally diagnosed cases?. Pediatr Radiol. 2005 Jan. 35(1):79-84. [QxMD MEDLINE Link].

43. Visrutaratna P, Euathrongchit J, Kattipattanapong V. Clinics in diagnostic imaging (86). Ruptured bronchogenic cyst. Singapore Med J. 2003 Jun. 44(6):325-9. [QxMD MEDLINE Link].

Anne E Stone, MD Assistant Professor of Pediatrics, Division of Pediatric Pulmonary Medicine, Weill Cornell Medical College

Anne E Stone, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, American Thoracic Society

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Charles Callahan, DO Professor, Chief, Department of Pediatrics and Pediatric Pulmonology, Tripler Army Medical Center

Charles Callahan, DO is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, American College of Osteopathic Pediatricians, American Thoracic Society, Association of Military Surgeons of the US, Christian Medical and Dental Associations

Disclosure: Nothing to disclose.

Denise Serebrisky, MD Associate Professor, Department of Pediatrics, Albert Einstein College of Medicine; Director, Division of Pulmonary Medicine, Lewis M Fraad Department of Pediatrics, Jacobi Medical Center/North Central Bronx Hospital; Director, Jacobi Asthma and Allergy Center for Children, Jacobi Medical Center

Denise Serebrisky, MD is a member of the following medical societies: American Thoracic Society

Disclosure: Nothing to disclose.

Michael R Bye, MD Professor of Clinical Pediatrics, State University of New York at Buffalo School of Medicine; Attending Physician, Pediatric Pulmonary Division, Women's and Children's Hospital of Buffalo

Michael R Bye, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, American Thoracic Society

Disclosure: Nothing to disclose.

Thomas Scanlin, MD Chief, Division of Pulmonary Medicine and Cystic Fibrosis Center, Department of Pediatrics, Rutgers Robert Wood Johnson Medical School

Thomas Scanlin, MD is a member of the following medical societies: American Association for the Advancement of Science, Society for Pediatric Research, American Society for Biochemistry and Molecular Biology, American Thoracic Society, Society for Pediatric Research

Disclosure: Nothing to disclose.

• Print this section
• Print the entire contents of
• Print the entire contents of article